Corpus ID: 87503765

Association between a polymorphism of aldosterone synthase gene and essential hypertension

@article{Dan2006AssociationBA,
  title={Association between a polymorphism of aldosterone synthase gene and essential hypertension},
  author={Chen Dan},
  journal={Journal of Dalian Medical University},
  year={2006}
}

• Chen Dan
• Published 2006
• Biology
• Journal of Dalian Medical University

[Objective]To investigate the association of the polymorphism of aldosterone synthase with essential hypertension(EH)in Dalian.[Method]Essential hypertensives 339 and healthy people 640 were enrolled into this study.The genome DNA was extracted in white blood cells.Polymerase chain reaction(PCR) and HaeⅢ restriction endonuclease digestion were employed to study C-344 T polymorphism of CYP11B2 gene.[Results]The frequency of CYP11B2-344C/T genotype in the hypertensive cohort and controls were CC… Expand

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