Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes.

@article{Qi2013AssociationBA,
  title={Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes.},
  author={Lu Qi and Qibin Qi and Sabrina Prudente and C. E. D'a. Mendonça and Francesco Andreozzi and Natalia di Pietro and Mariella Sturma and Valeria Novelli and Gaia Chiara Mannino and Gloria Formoso and Ernest V. Gervino and Thomas H. Hauser and Jochen Daniel Muehlschlegel and Monika A Niewczas and Andrzej S Krolewski and Gianni Biolo and Assunta Pandolfi and Eric B Rimm and Giorgio Sesti and Vincenzo Trischitta and Frank B Hu and Alessandro Doria},
  journal={JAMA},
  year={2013},
  volume={310 8},
  pages={
          821-8
        }
}
IMPORTANCE Diabetes is associated with an elevated risk of coronary heart disease (CHD). Previous studies have suggested that the genetic factors predisposing to excess cardiovascular risk may be different in diabetic and nondiabetic individuals. OBJECTIVE To identify genetic determinants of CHD that are specific to patients with diabetes. DESIGN, SETTING, AND PARTICIPANTS We studied 5 independent sets of CHD cases and CHD-negative controls from the Nurses' Health Study (enrolled in 1976… CONTINUE READING
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