Association between a deletion/insertion polymorphism in the α2B-adrenergic receptor gene and insulin secretion and Type 2 diabetes. The Finnish Diabetes Prevention Study

Abstract

Impaired insulin secretion has a strong genetic component. In this study we investigated whether the 12Glu9 polymorphism in the gene encoding the α2B-adrenergic receptor (ADRA2B) is associated with insulin secretion and/or the incidence of Type 2 diabetes in individuals with impaired glucose tolerance. We investigated a total of 506 subjects with impaired… (More)
DOI: 10.1007/s00125-004-1462-z

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@article{Siitonen2004AssociationBA, title={Association between a deletion/insertion polymorphism in the α2B-adrenergic receptor gene and insulin secretion and Type 2 diabetes. The Finnish Diabetes Prevention Study}, author={Niina Siitonen and J. Lindstr{\"o}m and J. Eriksson and Tania Valle and Harri H{\"a}m{\"a}l{\"a}inen and Pirjo Ilanne-Parikka and Sirkka Kein{\"a}nen-Kiukaanniemi and Jaakko O I Tuomilehto and M. Laakso and Matti Uusitupa}, journal={Diabetologia}, year={2004}, volume={47}, pages={1416-1424} }