Association between Regimen Composition and Treatment Response in Patients with Multidrug-Resistant Tuberculosis: A Prospective Cohort Study

@inproceedings{Yuen2015AssociationBR,
  title={Association between Regimen Composition and Treatment Response in Patients with Multidrug-Resistant Tuberculosis: A Prospective Cohort Study},
  author={Courtney M. Yuen and Ekaterina V. Kurbatova and Thelma E. Tupasi and Janice Campos Caoili and Martie L. van der Walt and Charlotte Kvasnovsky and Martin J. A. Yagui and Jaime Bayona and Carmen Contreras and Vaira Leimane and Julia V. Ershova and Laura E Via and Hee-jin Kim and Somsak Akksilp and Boris Y. Kazennyy and Grigory V. Volchenkov and Ruwen Jou and Kai Kliiman and Olga V. Demikhova and Irina A. Vasilyeva and Tracy L. Dalton and J. Peter Cegielski and Madhukar Pai},
  booktitle={PLoS medicine},
  year={2015}
}
BACKGROUND For treating multidrug-resistant tuberculosis (MDR TB), the World Health Organization (WHO) recommends a regimen of at least four second-line drugs that are likely to be effective as well as pyrazinamide. WHO guidelines indicate only marginal benefit for regimens based directly on drug susceptibility testing (DST) results. Recent evidence from isolated cohorts suggests that regimens containing more drugs may be beneficial, and that DST results are predictive of regimen effectiveness… CONTINUE READING
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Improving outcomes for multidrug-resistant tuberculosis: aggressive regimens prevent treatment failure and death.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2014
View 5 Excerpts
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Anti-tuberculosis drug resistance in Bangladesh: reflections from the first nationwide survey.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease • 2015
View 1 Excerpt

Concordance of Mycobacterium tuberculosis fluoroquinolone resistance testing: implications for treatment.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease • 2015
View 1 Excerpt

Extensive drug resistance acquired during treatment of multidrug-resistant tuberculosis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2014
View 2 Excerpts

Treatment outcomes and moxifloxacin susceptibility in ofloxacin-resistant multidrug-resistant tuberculosis.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease • 2014
View 1 Excerpt

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