Association between PON1 genetic polymorphisms and miscarriage in Mexican women exposed to pesticides.

@article{BlancoMuoz2013AssociationBP,
  title={Association between PON1 genetic polymorphisms and miscarriage in Mexican women exposed to pesticides.},
  author={Julia Blanco-Mu{\~n}oz and Clemente Aguilar-Gardu{\~n}o and Ricardo Gamboa-{\'A}vila and Miguel Rodr{\'i}guez-Barranco and {\'O}scar P{\'e}rez-M{\'e}ndez and Claudia Huesca-G{\'o}mez and Beatriz Gonz{\'a}lez-Alzaga and Marina Lacasa{\~n}a},
  journal={The Science of the total environment},
  year={2013},
  volume={449},
  pages={302-8}
}
BACKGROUND Placental oxidative stress has been involved in the pathogenesis of certain reproductive adverse effects, including miscarriage. Paraxonase 1 (PON1) is a high-density lipoprotein(HDL)-linked enzyme that prevents oxidation of low-density lipoproteins (LDL) and is involved in detoxification from organophosphate pesticides. OBJECTIVE To assess the association between maternal PON1 polymorphisms (PON1192Q/R, PON155 L/M y PON1-108C/T) and the risk of miscarriage in women chronically… CONTINUE READING
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Maternal exposure to fl oricultural work during pregnancy , PON 1 Q 192 R polymorphisms and the risk of low birth weight

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