Association between Oxidative Stress and Outcome in Different Subtypes of Acute Ischemic Stroke

  title={Association between Oxidative Stress and Outcome in Different Subtypes of Acute Ischemic Stroke},
  author={Nai-Wen Tsai and Ya-Ting Chang and Chi-Ren Huang and Y. Lin and Wei-Che Lin and Ben-Chung Cheng and Chih-Min Su and Yi-Fang Chiang and Shu-Fang Chen and Chin-Cheng Huang and Wen-Neng Chang and Cheng-Hsien Lu},
  booktitle={BioMed research international},
OBJECTIVES This study investigated serum thiobarbituric acid-reactive substances (TBARS) and free thiol levels in different subtypes of acute ischemic stroke (AIS) and evaluated their association with clinical outcomes. METHODS This prospective study evaluated 100 AIS patients, including 75 with small-vessel and 25 with large-vessel diseases. Serum oxidative stress (TBARS) and antioxidant (thiol) were determined within 48 hours and days 7 and 30 after stroke. For comparison, 80 age- and sex… CONTINUE READING
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