Association between Methylenetetrahydrofolate Reductase C677T Polymorphism and Bone Mineral Density: The Dong-gu Study and the Namwon Study

@inproceedings{Shin2013AssociationBM,
  title={Association between Methylenetetrahydrofolate Reductase C677T Polymorphism and Bone Mineral Density: The Dong-gu Study and the Namwon Study},
  author={Min Ho Shin and Jin-Su Choi and Jung-Ae Rhee and Young Hoon Lee and Hae Sung Nam and Seul-Ki Jeong and Kyeong-Soo Park and Hye-Yeon Kim and So Yeon Ryu and Seong-Woo Choi and Hye-rim Song and Hee Nam Kim and Jane A. Cauley and Sun Seog Kweon},
  booktitle={Journal of Korean medical science},
  year={2013}
}
The purpose of this study was to examine the association between the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and bone mineral density (BMD). Two large cohort studies were performed: the Dong-gu Study (3,621 men and 5,409 women) and the Namwon Study (3,703 men and 5,672 women). We assessed lumbar spine and femoral neck BMD by dual-energy X-ray absorptiometry. Genotypes were determined by real-time polymerase chain reaction. Multiple linear regression analysis was performed… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

References

Publications referenced by this paper.
Showing 1-10 of 23 references

Low dietary riboflavin but not folate predicts increased fracture risk in postmenopausal women homozygous for the MTHFR 677 T allele.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research • 2008
View 6 Excerpts
Highly Influenced

Cohort Profile: The Namwon Study and the Dong-gu Study.

International journal of epidemiology • 2014
View 1 Excerpt

Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research • 2007
View 2 Excerpts

Homocysteine enhances bone resorption by stimulation of osteoclast formation and activity through increased intracellular ROS generation.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research • 2006
View 1 Excerpt

mass in Danish men : results from the Odense Androgen Study

M Li, EM Lau, J Woo
2006

Similar Papers

Loading similar papers…