Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes

@inproceedings{Lee2017AssociationBM,
  title={Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes},
  author={Eun Young Lee and Sena Hwang and Yong-Ho Lee and Seo Hee Lee and Young Mi Lee and Hua Pyong Kang and Eugene Han and Woonhyoung Lee and Byung-Wan Lee and Eun Seok Kang and Bong Soo Cha and Hyun Chul Lee},
  booktitle={Yonsei medical journal},
  year={2017}
}
PURPOSE Metformin can reduce diabetes-related complications and mortality. However, its use is limited because of potential lactic acidosis-associated adverse effects, particularly in renal impairment patients. We aimed to investigate the association of metformin use with lactic acidosis and hyperlactatemia in patients with type 2 diabetes. MATERIALS AND METHODS This was a cross-sectional study from a tertiary university-affiliated medical center. A total of 1954 type 2 diabetes patients were… CONTINUE READING
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