Association between MTHFR 677C>T Polymorphism and Vitamin B12 Deficiency: A Case-control Study

@inproceedings{AlBatayneh2018AssociationBM,
  title={Association between MTHFR 677C>T Polymorphism and Vitamin B12 Deficiency: A Case-control Study},
  author={Khalid M. Al-Batayneh and Mazhar Salim Al Zoubi and M. Shamir Shehab and Bahaa Al-Trad and Khaldon Bodoor and Wesam Al Khateeb and Alaa A A Aljabali and Mohammad Hamad and Greg J Eaton},
  booktitle={Journal of medical biochemistry},
  year={2018}
}
Background Vitamin B12 (cobalamin) deficiency is a prevalent worldwide health concern. Several factors are associated with vitamin B12 deficiency including lifestyle, genetic predisposition, and malfunctions in the absorption and transport of vitamin B12. In the current case-control study, we aimed at investigating the association between MTHFR polymorphisms and vitamin B12 deficiency in a Jordanian population. Methods Two polymorphic sites of the MTHFR gene (c.677C>T, rs1801133 and c.1286A>C… CONTINUE READING

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