Association between IL17A/IL17RA Gene Polymorphisms and Susceptibility to Alopecia Areata in the Korean Population

@inproceedings{Lew2012AssociationBI,
  title={Association between IL17A/IL17RA Gene Polymorphisms and Susceptibility to Alopecia Areata in the Korean Population},
  author={Bark-Lynn Lew and H R Cho and Sik Haw and Hwi-Jun Kim and Joo-Ho Chung and W S Sim},
  booktitle={Annals of dermatology},
  year={2012}
}
BACKGROUND Alopecia areata is marked by autoimmune assault on the hair follicle resulting in hair loss. T helper 17 cell subset has important roles in protecting the host against extracellular pathogens, however, also promotes inflammatory pathology in autoimmune disease, and it expresses both interleukin (IL)-17A and IL-17F, which can signal via the IL-17 receptor A. OBJECTIVE To investigate the significance of IL17A and IL17RA gene polymorphisms in the susceptibility to alopecia areata… CONTINUE READING