Association between IL-1beta -511C/T and IL-1RA (86bp)n repeats polymorphisms and schizophrenia.

@article{Zanardini2003AssociationBI,
  title={Association between IL-1beta -511C/T and IL-1RA (86bp)n repeats polymorphisms and schizophrenia.},
  author={R. A. D. Zanardini and Luisella Bocchio-Chiavetto and Catia Scassellati and Cristian Bonvicini and Gian Battista Tura and Giuseppe Rossi and J. Zu{\~n}iga P{\'e}rez and Massimo Gennarelli},
  journal={Journal of psychiatric research},
  year={2003},
  volume={37 6},
  pages={457-62}
}
It has been established that cytokines play a critical role in the regulation of the CNS and recent studies have suggested that dysfunctions of both pro-inflammatory (IL-1beta, IL-6, and TNF-alpha) and anti-inflammatory (IL-1RA and IL-10) cytokines could be involved in the pathophysiology of schizophrenia. Previous studies have reported that functional polymorphisms in some cytokines genes may have important regulatory effects on such system. Therefore, the aim of the present study was to… CONTINUE READING
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