Association between HLA Class I and Class II Alleles and the Outcome of West Nile Virus Infection: An Exploratory Study

@inproceedings{Lanteri2011AssociationBH,
  title={Association between HLA Class I and Class II Alleles and the Outcome of West Nile Virus Infection: An Exploratory Study},
  author={Marion Christine Lanteri and Zhanna Kaidarova and Trevor A Peterson and Steven Cate and Brian Custer and Shiquan Wu and Maria Agapova and Jacqueline P. Law and Thomas Bielawny and Frank Plummer and Leslie H. H. Tobler and Mark Loeb and Michael P. Busch and Jonathan L Bramson and Ma Luo and Phillip J Norris},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND West Nile virus (WNV) infection is asymptomatic in most individuals, with a minority developing symptoms ranging from WNV fever to serious neuroinvasive disease. This study investigated the impact of host HLA on the outcome of WNV disease. METHODS A cohort of 210 non-Hispanic mostly white WNV(+) subjects from Canada and the U.S. were typed for HLA-A, B, C, DP, DQ, and DR. The study subjects were divided into three WNV infection outcome groups: asymptomatic (AS), symptomatic (S… CONTINUE READING
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