Association between EGF, TGF-β1 and TNF-α gene polymorphisms and hepatocellular carcinoma.

  title={Association between EGF, TGF-β1 and TNF-α gene polymorphisms and hepatocellular carcinoma.},
  author={H Shi and Peng Ren and Qing-Jun Lu and Marco Niedrgethmnn and Guo-yang Wu},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  volume={13 12},
INTRODUCTION Up to present, EGF 61*A/G, TGF-β1 -509*T/C and TNF-α -308*A/G gene polymorphisms have been analysed in other cancer entities than hepatocellular carcinoma (HCC). We here investigated the frequency of these gene polymorphisms among HCC patients. MATERIALS AND METHODS A total of 73 HCC patients and 117 cancer-free healthy people were recruited at the Surgical Department of Zhongshan Hospital. Genomic DNA was isolated from peripheral blood and gene polymorphisms were analyzed by PCR… CONTINUE READING
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