Association between DNA methylation of SORL1 5'-flanking region and mild cognitive impairment in type 2 diabetes mellitus.

@article{Yu2016AssociationBD,
  title={Association between DNA methylation of SORL1 5'-flanking region and mild cognitive impairment in type 2 diabetes mellitus.},
  author={Yang Yu and Wang Mingjiao and Xiaohui Yang and Miao Sui and Tong Zhang and Jin Peng Liang and Xinyi Gu and Xiaowei Wang},
  journal={Annales d'endocrinologie},
  year={2016},
  volume={77 6},
  pages={
          625-632
        }
}
OBJECTIVES In the present study, we examined whether DNA methylation of the sortilin-related receptor 1 (SORL1) 5'-flanking region is associated with the manifestation and clinical presentation of mild cognitive impairment in type 2 diabetes mellitus (T2DM). METHODS Of 84 diabetic patients with mild cognitive impairment (MCI group), 78 diabetic patients without mild cognitive impairment (NMCI group) and 80 age-matched normal controls (NC group), the DNA methylation of the SORL1 5'-flanking… CONTINUE READING
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