Association between CYP19 polymorphisms and breast cancer risk: results from 10,592 cases and 11,720 controls

@article{Ma2009AssociationBC,
  title={Association between CYP19 polymorphisms and breast cancer risk: results from 10,592 cases and 11,720 controls},
  author={Xiangyu Ma and Xiaowei Qi and Chunhai Chen and Hui Lin and Hongyan Xiong and Yafei Li and Jingqian Liu},
  journal={Breast Cancer Research and Treatment},
  year={2009},
  volume={122},
  pages={495-501}
}
The association of CYP19 gene polymorphisms with breast cancer has been widely reported, but results of previous studies were somewhat contradictory and underpowered. In order to overcome the limitations of individual study and to understand the real situation, we conducted a systematic review and meta-analysis including three CYP19 gene polymorphisms [R264C polymorphism, CYP19_630 3-bp del/Ins polymorphism, and CYP19_681 (TTTA)n polymorphisms]. A total of 22 studies with 10,592 cases and 11… CONTINUE READING