Association between Arg399Gln polymorphism of X-ray repair cross-complementing 1 (XRCC1) gene and sporadic endometrial cancer in the Polish population.

@article{Samulak2011AssociationBA,
  title={Association between Arg399Gln polymorphism of X-ray repair cross-complementing 1 (XRCC1) gene and sporadic endometrial cancer in the Polish population.},
  author={Dariusz Samulak and Hanna Romanowicz-Makowska and Beata Smolarz and Andrzej Kulig and Stanisław Sporny},
  journal={European journal of gynaecological oncology},
  year={2011},
  volume={32 5},
  pages={491-5}
}
BACKGROUND Endometrial cancer is one of the most common malignant neoplasms which appear in the uterine body. X-ray repair cross-complementing 1 (XRCC1) protein can be involved in the repair of DNA lesions, which are known to contribute to endometrial cancer. MATERIAL AND METHODS The genotype analysis of XRCC1 Arg399Gln gene polymorphisms for 456 endometrial cancer patients and 300 controls of cancer-free subjects in the Polish population were performed using the PCR-based restriction… CONTINUE READING