Association between Amygdala Hyperactivity to Harsh Faces and Severity of Social Anxiety in Generalized Social Phobia

@article{Phan2006AssociationBA,
  title={Association between Amygdala Hyperactivity to Harsh Faces and Severity of Social Anxiety in Generalized Social Phobia},
  author={K. L. Phan and D. Fitzgerald and P. Nathan and M. Tancer},
  journal={Biological Psychiatry},
  year={2006},
  volume={59},
  pages={424-429}
}
  • K. L. Phan, D. Fitzgerald, +1 author M. Tancer
  • Published 2006
  • Medicine, Psychology
  • Biological Psychiatry
  • BACKGROUND Previous functional brain imaging studies of social anxiety have implicated amygdala hyperactivity in response to social threat, though its relationship to quantitative measures of clinical symptomatology remains unknown. The primary aim of this study was to examine the association between response to emotionally harsh faces in the amygdala, a region implicated in social and threat-related processing, and severity of social anxiety symptoms in patients with generalized social phobia… CONTINUE READING
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    References

    SHOWING 1-10 OF 49 REFERENCES
    Neurobiological mechanisms of social anxiety disorder.
    • 120
    • PDF
    The human amygdala and the emotional evaluation of sensory stimuli
    • D. Zald
    • Psychology, Medicine
    • Brain Research Reviews
    • 2003
    • 1,018
    • PDF
    Social anxiety disorder
    • 17
    • PDF