Association between Alzheimer’s Disease and Apolipoprotein E Polymorphisms

  title={Association between Alzheimer’s Disease and Apolipoprotein E Polymorphisms},
  author={Elnaz Gozalpour and Koosha Kamali and K Mohammd and H R K Khorshid and Mina Ohadi and Masood Karimloo and Arash Mirabzadeh and Akbar Fotouhi},
  booktitle={Iranian journal of public health},
BACKGROUND Alzheimer's disease as a neurodegenerative disorder is the commonest type of dementia. A growing number of genes have been reported as the risk factors, which increase the susceptibility to Alzheimer's disease. Apolipoprotein E (APOE), which its ε4 allele has been reported as a risk factor in late onset Alzheimer's disease (AD), is the main cholesterol carrier in the brain. The main goal of this study was to assess the role of APOE genotypes and alleles in AD in Iranian population… CONTINUE READING

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