Association between -799C/T single nucleotide polymorphism of the MMP‑8 promoter region and thoracic aortic dissection.

Abstract

Thoracic aortic dissection (TAD) is a life-threatening vascular condition, in which matrix metalloproteinases (MMPs) are involved. Since the key determinants underlying MMP action remain elusive, the present study investigated the correlation between single nucleotide polymorphisms (SNPs) in the promoter region of the MMP‑8 gene and a predisposition to TAD… (More)
DOI: 10.3892/mmr.2014.2437

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