Association between -1438G/A promoter polymorphism in the 5-HT(2A) receptor gene and fluvoxamine response in Japanese patients with major depressive disorder.

Abstract

Genetic polymorphism of the serotonin 5-HT(2A) receptor seems to be associated with therapeutic response to selective serotonin reuptake inhibitors (SSRIs). The present study investigated whether a novel -1438G/A polymorphism in the promoter region of the 5-HT(2A )receptor gene is associated with therapeutic response to fluvoxamine (an SSRI) in 66 Japanese… (More)

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@article{Sato2002AssociationB, title={Association between -1438G/A promoter polymorphism in the 5-HT(2A) receptor gene and fluvoxamine response in Japanese patients with major depressive disorder.}, author={Kazuhiro Sato and Keizo Yoshida and Hitoshi Takahashi and Kenichi Ito and Mitsuhiro Kamata and Hisashi Higuchi and Tetsuo Shimizu and Kunihiko Itoh and Kazuyuki Inoue and Takehiko Tezuka and Toshio Suzuki and Taashi Ohkubo and Kazunobu Sugawara and Koichi Otani}, journal={Neuropsychobiology}, year={2002}, volume={46 3}, pages={136-40} }