Association and interaction of PPARα, δ, and γ gene polymorphisms with low-density lipoprotein-cholesterol in a Chinese Han population.

@article{Fan2015AssociationAI,
  title={Association and interaction of PPARα, δ, and γ gene polymorphisms with low-density lipoprotein-cholesterol in a Chinese Han population.},
  author={Wei Fan and Chao Shen and Ming Wu and Zheng-yuan Zhou and Zhi-rong Guo},
  journal={Genetic testing and molecular biomarkers},
  year={2015},
  volume={19 7},
  pages={379-86}
}
AIMS Elevated low-density lipoprotein-cholesterol (LDL-C) is regarded as one of major risks of cardiovascular diseases and atherosclerotic events. It has been previously reported that peroxisome proliferator-activated receptors (PPARs) play an important role in the regulation of lipid metabolism. In this study, we aimed to investigate the influence of PPARα/δ/γ gene polymorphisms on LDL-C level. Eight hundred twenty unrelated participants were recruited. Ten single-nucleotide polymorphisms… CONTINUE READING

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