Association and gene-gene interactions of eight common single-nucleotide polymorphisms with pediatric asthma in middle china.

@article{Wu2010AssociationAG,
  title={Association and gene-gene interactions of eight common single-nucleotide polymorphisms with pediatric asthma in middle china.},
  author={Xiaohui Wu and Yirong Li and Qingguo Chen and Fenghua Chen and Pengcheng Cai and Lin Wang and Lihua Hu},
  journal={The Journal of asthma : official journal of the Association for the Care of Asthma},
  year={2010},
  volume={47 3},
  pages={238-44}
}
BACKGROUND Asthma is a common polygenic disease, caused by complex interactions between multiple genes and environmental factors. Study of the gene-gene interactions would contribute to a new insight into the pathogenesis and therapeutics of asthma. OBJECTIVE To evaluate the single and combined associations of eight single-nucleotide polymorphisms loci in five candidate genes with the development of asthma in Chinese children. METHODS We examined eight single-nucleotide polymorphisms (SNPs… CONTINUE READING
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