Association and colocalization of K+ channel alpha- and beta-subunit polypeptides in rat brain.

@article{Rhodes1995AssociationAC,
  title={Association and colocalization of K+ channel alpha- and beta-subunit polypeptides in rat brain.},
  author={Kenneth J. Rhodes and S A Keilbaugh and Nestor X. Barrezueta and Kristin Lopez and James S Trimmer},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1995},
  volume={15 7 Pt 2},
  pages={5360-71}
}
Recent cloning of auxiliary subunits associated with voltage-gated ion channels and their subsequent coexpression with the channel forming alpha-subunits has revealed that the expression level, gating and conductance properties of the expressed channels can be profoundly affected by the presence of an auxiliary subunit polypeptide. In the present study, we raised antibodies against the beta-subunit associated with the bovine dendrotoxin sensitive K(+)-channel complex and used these antibodies… CONTINUE READING