Association and Prognostic Significance of the Functional −1562C/T Polymorphism in the Promoter Region of MMP-9 in Turkish Patients with Gastric Cancer

Abstract

Matrix metalloproteinases (MMPs) are a group of zinc-dependent peptidases that participate in matrix turnover in solid malignancies. The aim of this study was twofold. First, we sought to investigate under a case–control design the association between the functional −1562C/T polymorphism in the promoter region of MMP-9 and gastric cancer (GC) in a Turkish… (More)
DOI: 10.1007/s12253-015-9950-7

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