Association analysis of the −308G > A promoter polymorphism of the tumor necrosis factor alpha (TNF-α) gene in Japanese patients with schizophrenia

@article{Hashimoto2004AssociationAO,
  title={Association analysis of the −308G > A promoter polymorphism of the tumor necrosis factor alpha (TNF-α) gene in Japanese patients with schizophrenia},
  author={Ryota Hashimoto and Masaharu Yoshida and Norio Ozaki and Yoshio Yamanouchi and Nakao Iwata and Tatsuyo Suzuki and Tsuyoshi Kitajima and Masahiko Tatsumi and Kunitoshi Kamijima and Hiroshi Kunugi},
  journal={Journal of Neural Transmission},
  year={2004},
  volume={111},
  pages={217-221}
}
Two research groups have thus far reported a significant association between schizophrenia and a promoter polymorphism (−308G > A) of the gene encoding tumor necrosis factor alpha (TNF-α), while contradictive negative results have also been reported. We examined the possible association in a Japanese sample of 297 schizophrenia cases and 458 controls… CONTINUE READING