Association analysis of genetic polymorphisms and potential interaction of the osteocalcin (BGP) and ER-α genes with body mass index (BMI) in premenopausal Chinese women

Abstract

Introduction Obesity is a serious and complex disease worldwide. Body mass index (BMI), defined as weight in kilograms divided by the square of height in meters, is a WHO standard index for obesity. BMI is under strong genetic determination with heritability ranging from 20% to 90%. Although genetic factors have a clear role in determining BMI variations… (More)

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