Association analyses of genetic polymorphisms of GSTM1, GSTT1, NQO1, NAT2, LPL, PRSS1, PSTI, and CFTR with chronic alcoholic pancreatitis in Japan.

@article{Maruyama2010AssociationAO,
  title={Association analyses of genetic polymorphisms of GSTM1, GSTT1, NQO1, NAT2, LPL, PRSS1, PSTI, and CFTR with chronic alcoholic pancreatitis in Japan.},
  author={Katsuya Maruyama and Shoji Harada and Akira Yokoyama and Satoshi Mizukami and Satoru Naruse and Masahiko Hirota and Isao Nishimori and Makoto Otsuki},
  journal={Alcoholism, clinical and experimental research},
  year={2010},
  volume={34 Suppl 1},
  pages={S34-8}
}
BACKGROUND Excessive consumption of alcohol is involved in the onset of pancreatitis. However, most of heavy drinkers do not always develop chronic pancreatitis. Various genetic factors appear to be involved in these individual differences in onset of chronic alcoholic pancreatitis. Here we investigated a possible association of alcoholic pancreatitis with polymorphisms of the various genes belong to the phase II detoxification enzymes responsible for metabolism of the oxidative compounds, and… CONTINUE READING