Association among Fas expression in leucocytes, serum Fas and Fas-ligand concentrations and hepatic inflammation and fibrosis in chronic hepatitis C.

@article{Panasiuk2010AssociationAF,
  title={Association among Fas expression in leucocytes, serum Fas and Fas-ligand concentrations and hepatic inflammation and fibrosis in chronic hepatitis C.},
  author={Anatol Panasiuk and Anna Parfieniuk and Janusz Zak and R Flisiak},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  year={2010},
  volume={30 3},
  pages={472-8}
}
BACKGROUND Replication of the hepatitis C virus (HCV) in peripheral blood mononuclear cells (PBMC) may impair immune functions and establish persistent infection. The aim of this study was to assess the influence of HCV on PBMC and their susceptibility to apoptosis in relation to liver inflammation and fibrosis. METHODS Eighty-one patients with chronic hepatitis C (CHC) were enrolled in this study. Flow cytometry was used to determine the amount of T cells (CD4(+), CD8(+)), B cells (CD19… CONTINUE READING