Association Between the 4p16 Susceptibility Locus and the Risk of Atrial Septal Defect in Population from Southeast China

@article{Pei2015AssociationBT,
  title={Association Between the 4p16 Susceptibility Locus and the Risk of Atrial Septal Defect in Population from Southeast China},
  author={Kaiyan Pei and Qiuyu Huang and Guican Zhang and Cailing Lu and Benzhang Yu and Liping Wu Yang},
  journal={Pediatric Cardiology},
  year={2015},
  volume={37},
  pages={120-124}
}
Three single nucleotide polymorphisms (SNPs), rs16835979, rs870142 and rs6824295, located in chromosome 4p16 were associated with the risk of ostium secundum atrial septal defect (ASD) in the European population. The 4p16 susceptibility locus in congenital heart disease was replicated in Chinese populations. Here, we analyzed the associations between these… CONTINUE READING