Association Between Younger Age and Targetable Genomic Alterations and Prognosis in Non-Small-Cell Lung Cancer.

@article{Sacher2016AssociationBY,
  title={Association Between Younger Age and Targetable Genomic Alterations and Prognosis in Non-Small-Cell Lung Cancer.},
  author={Adrian G. Sacher and Suzanne E Dahlberg and Jennifer C. Heng and Stacy L. Mach and Pasi Antero J{\"a}nne and Geoffrey R. Oxnard},
  journal={JAMA oncology},
  year={2016},
  volume={2 3},
  pages={
          313-20
        }
}
IMPORTANCE Non-small-cell lung cancer (NSCLC) diagnosed in young patients is rare, and the genomics and clinical characteristics of this disease are poorly understood. In contrast, the diagnosis of other cancers at a young age has been demonstrated to define unique disease biology. Herein, we report on the association of young age with targetable genomic alterations and prognosis in a cohort of 2237 patients with NSCLC. OBJECTIVE To determine the relationship between young age at diagnosis… CONTINUE READING
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