Association Between UrinaryMarkers of Nucleic Acid Oxidation andMortality in Type 2 Diabetes A population-based cohort study

Abstract

OBJECTIVEdWe recently showed that RNA oxidation, estimated by urinary excretion of 8-oxo-7,8-dihydroguanosine (8-oxoGuo), independently predicted mortality in a cohort of 1,381 treatment-naive patients with newly diagnosed type 2 diabetes. In the present investigation, we analyzed urine collected 6 years after the diagnosis to assess the association between… (More)

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