Association Between Urinary Type IV Collagen Level and Deterioration of Renal Function in Type 2 Diabetic Patients Without Overt Proteinuria

@inproceedings{Araki2010AssociationBU,
  title={Association Between Urinary Type IV Collagen Level and Deterioration of Renal Function in Type 2 Diabetic Patients Without Overt Proteinuria},
  author={Shin-Ichi Araki and Mitsuaki Haneda and Daisuke Koya and Keiji Isshiki and Shinji Kume and Toshiro Sugimoto and Hiroshige Kawai and Yoshihiko Nishio and Atsunori Kashiwagi and Takashi Uzu and Hiroshi Maegawa},
  booktitle={Diabetes care},
  year={2010}
}
OBJECTIVE Cross-sectional studies have reported increased levels of urinary type IV collagen in diabetic patients with progression of diabetic nephropathy. The aim of this study was to determine the role of urinary type IV collagen in predicting development and progression of early diabetic nephropathy and deterioration of renal function in a longitudinal study. RESEARCH DESIGN AND METHODS Japanese patients with type 2 diabetes (n = 254, 185 with normoalbuminuria and 69 with microalbuminuria… CONTINUE READING

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