Association Between Polymorphisms in the Dopamine Transporter Gene and Depression

  title={Association Between Polymorphisms in the Dopamine Transporter Gene and Depression},
  author={Gerald J. Haeffel and Marya Getchell and R. Koposov and C. Yrigollen and Colin G. De Young and B. A. Klinteberg and L. Oreland and V. Ruchkin and E. Grigorenko},
  journal={Psychological Science},
  pages={62 - 69}
  • Gerald J. Haeffel, Marya Getchell, +6 authors E. Grigorenko
  • Published 2008
  • Psychology, Medicine
  • Psychological Science
  • Previous research has generated examples of how genetic and environmental factors can interact to create risk for psychopathology. Using a gene-by-environment (G X E) interaction design, we tested whether three polymorphisms in the dopamine transporter gene (DAT1, also referred to as SLC6A3, located at 5p15.33) interacted with maternal parenting style to predict first-onset episodes of depression. Participants were male adolescents (N = 176) recruited from a juvenile detention center in… CONTINUE READING
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