Association Between Plasma Monocyte Chemoattractant Protein-1 Concentration and Cardiovascular Disease Mortality in Middle-Aged Diabetic and Nondiabetic Individuals

@inproceedings{Piemonti2009AssociationBP,
  title={Association Between Plasma Monocyte Chemoattractant Protein-1 Concentration and Cardiovascular Disease Mortality in Middle-Aged Diabetic and Nondiabetic Individuals},
  author={Lorenzo Piemonti and Giliola Calori and Guido Lattuada and Alessia Mercalli and Francesca Ragogna and Maria Paola Garancini and Giacomo Ruotolo and Livio Luzi and Gianluca Perseghin},
  booktitle={Diabetes care},
  year={2009}
}
OBJECTIVE Monocyte chemoattractant protein-1 (MCP-1/CCL2) is a chemokine involved into the pathogenesis of atherosclerosis and has prognostic value in the acute and chronic phases in patients with acute coronary syndromes. RESEARCH DESIGN AND METHODS MCP-1/CCL2 concentration was measured in plasma fractions of 363 middle-aged overweight/obese individuals (aged 61 +/- 12 years, BMI 30.1 +/- 6.6 kg/m(2), 15% with type 2 diabetes, and 12% with impaired glucose tolerance) of a population survey… CONTINUE READING

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