Associate PCR-RFLP Assay Design With SNPs Based on Genetic Algorithm in Appropriate Parameters Estimation

@article{Chuang2013AssociatePA,
  title={Associate PCR-RFLP Assay Design With SNPs Based on Genetic Algorithm in Appropriate Parameters Estimation},
  author={Li-Yeh Chuang and Yu-Huei Cheng and Cheng-Huei Yang and Cheng-Hong Yang},
  journal={IEEE Transactions on NanoBioscience},
  year={2013},
  volume={12},
  pages={119-127}
}
Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is a commonly used laboratory technique and useful in small-scale basic research studies of complex genetic diseases that are associated with single nucleotide polymorphisms (SNPs). Before PCR-RFLP assay for SNP genotyping can be performed, a feasible primer pair observes numerous… CONTINUE READING