Assisted reproductive technology and complex chromosomal rearrangements: the limits of ICSI.

  title={Assisted reproductive technology and complex chromosomal rearrangements: the limits of ICSI.},
  author={J P Siffroi and Brigitte Benzacken and Bernd Straub and Corine Le Bourhis and Marie Odile North and G Curotti and V{\'e}ronique Bellec and Susana Subir{\`a} {\'A}lvarez and J. P. Dadoune},
  journal={Molecular human reproduction},
  volume={3 10},
Complex chromosomal rearrangements are very rare events in the human population. According to our knowledge on the consequences of simple reciprocal translocations for male fertility, translocations involving three or more chromosomes are thought to lead to severe reproductive impairments in terms of meiotic disturbance or chromosomal imbalance of gametes. We report the case of a 48 year old man whose sperm count revealed either oligozoospermia (<10(3) spermatozoa/ml) or azoospermia. He was… CONTINUE READING
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