Assisted reproduction and thyroid autoimmunity: an unfortunate combination?

@article{Poppe2003AssistedRA,
  title={Assisted reproduction and thyroid autoimmunity: an unfortunate combination?},
  author={Kris Poppe and Daniel Glinoer and Herman J. Tournaye and Paul Devroey and Andr{\'e} C. van Steirteghem and Leonard Kaufman and Brigitte Velkeniers},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2003},
  volume={88 9},
  pages={4149-52}
}
The association between positive thyroid antibodies and an increased miscarriage rate in pregnancies after assisted reproduction technology (ART) remains controversial. We wanted to clarify this issue by performing a prospective cohort study in 234 women by systematically screening for thyroid peroxidase antibodies (TPO-Ab), serum TSH, and free T(4)(FT(4)) before the first ART cycle. Women with overt thyroid dysfunction were excluded. Fourteen percent of the cohort had positive TPO-Ab. Baseline… CONTINUE READING

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