Assignment1 of the Smad7 gene (MADH7) to human chromosome 18q21.1 by fluorescence in situ hybridization

@article{Rijer1998Assignment1OT,
  title={Assignment1 of the Smad7 gene (MADH7) to human chromosome 18q21.1 by fluorescence in situ hybridization},
  author={E. R{\"o}ijer and A. Morén and P. ten Dijke and G. Stenman},
  journal={Cytogenetic and Genome Research},
  year={1998},
  volume={81},
  pages={189 - 190}
}
TGF-ß family members elicit their multifunctional effects on target cells via distinct complexes of type I and type II serine/threonine kinase receptors (Heldin et al., 1997). Smad family members are key components in the intracellular signaling pathway of TGF-ß family members (Heldin et al., 1997; Massagué et al., 1997). Certain Smads, e.g., Smad2, Smad3 and Smad5, are pathway-restricted and transiently interact with and become phosphorylated by specific type I receptor kinases (Heldin et al… Expand
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