Assignment1 of FRA1H common fragile site to human chromosome band 1q42.1 proximal to the nuclear NAD+ ADP-ribosyltransferase gene (ADPRT) and to the main 5S rRNA gene locus

  title={Assignment1 of FRA1H common fragile site to human chromosome band 1q42.1 proximal to the nuclear NAD+ ADP-ribosyltransferase gene (ADPRT) and to the main 5S rRNA gene locus},
  author={Franca Pelliccia and Maria Zaira Limongi and Lucia Gaddini and Angela Rocchi},
  journal={Cytogenetic and Genome Research},
  pages={121 - 122}
The DAPI-inducible human common fragile site that cytologically corresponds to the 5-azacytidine inducible site FRA1H is located at chromosome region 1q42 (Pelliccia and Rocchi, 1986; Sutherland et al., 1985). In the same region, a locus implicated in coding NAD+ ADP-ribosyl transferase (ADPRT alias PARP) (Baumgartner et al.,1992), and the main cluster of the 5S rRNA genes (Lomholt et al., 1995) have been mapped. In this work we have simultaneously mapped and ordered these three markers. Common… 

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