Assignment of the porcine hyaluronidase-3 (HYAL3) gene to SSC13-->q21 by FISH and confirmation by hybrid panel analyses.

@article{Gatphayak2003AssignmentOT,
  title={Assignment of the porcine hyaluronidase-3 (HYAL3) gene to SSC13-->q21 by FISH and confirmation by hybrid panel analyses.},
  author={Kesinee Gatphayak and Christoph Knorr and Felix A. Habermann and Ruedi Fries and Bertram Brenig},
  journal={Cytogenetic and genome research},
  year={2003},
  volume={101 2},
  pages={178}
}
Hyaluronidases are enzymes responsible for the breakdown of hyaluronan (HA). The human genome contains six hyaluronidase-like genes sharing about 40% amino acid identity with one another. The genes are organized into two groups: HYAL1, HYAL2, and HYAL3 are clustered on HSA3p21.3 and are equivalent to the genes for tumor suppressor for small cell lung carcinoma LUCA1, LUCA2, and LUCA3, respectively (Wei et al., 1996). This cluster has been reported to be part of the Tumor Suppressor Genes clone… CONTINUE READING
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