Assignment of the human CC chemokine MPIF-2/eotaxin-2 (SCYA24) to chromosome 7q11.23.

@article{Nomiyama1998AssignmentOT,
  title={Assignment of the human CC chemokine MPIF-2/eotaxin-2 (SCYA24) to chromosome 7q11.23.},
  author={H. Nomiyama and L. Osborne and T. Imai and J. Kusuda and R. Miura and L. Tsui and O. Yoshie},
  journal={Genomics},
  year={1998},
  volume={49 2},
  pages={
          339-40
        }
}

Topics from this paper

Review: Immune Markers in Breast Milk and Fetal and Maternal Body Fluids: A Systematic Review of Perinatal Concentrations
Breastfeeding represents the continued exposure of the infant to the maternal immune environment. Uterine, perinatal, and postnatal exposure to immune factors may contribute to an infant’s risk ofExpand
CCL24 Signaling in the Tumor Microenvironment.
  • Sung-Jig Lim
  • Medicine
  • Advances in experimental medicine and biology
  • 2021
TLDR
C-C motif chemokine ligand 24 (CCL24) has been shown to contribute to tumorigenesis as well as inflammatory diseases like asthma, allergies, and eosinophilic esophagitis. Expand
A personalized approach to chronic rhinosinusitis with nasal polyps : based on biomarkers, phenotypes and new surgical thinking
TLDR
It is evident that carefully chosen biomarkers in combination with clinical characteristics can be used to identify type 2 CRSwNP, and treatment with dupilumab, a mAb directed to the IL-4Receptor a, reduces local type 2 inflammatory parameters in nasal secretions and nasal polyp tissue. Expand
An Overlook to the Characteristics and Roles Played by Eotaxin Network in the Pathophysiology of Food Allergies: Allergic Asthma and Atopic Dermatitis
TLDR
It is proposed that eotaxins (CCL11, CCL24, and CCL26) play key role(s) during symptomatic inflammatory responses raised in response to allergic crisis of these two clinical states. Expand
Chapter 44 – Mucosal Eosinophils
TLDR
Taken together, the eosinophils is both a key regulator and effector that is present in the circulation and mucosal immune system and specialized to launch a Th2-tilted response. Expand
Effect and mechanism of lipopolysaccharide on allergen-induced interleukin-5 and eotaxins production by whole blood cultures of atopic asthmatics
TLDR
The differential responses of the eotaxin family to specific antigens suggest that the predominant role of eotAXin‐2 and LPS may attenuate eosinophilic inflammation by inhibiting IL‐5 and eOTaxin‐1 and 3 synthesis through IL‐10 production. Expand
Association of eotaxin-2 gene polymorphisms with plasma eotaxin-2 concentration
TLDR
The susceptibility of patients with asthma to high eotaxin-2 production may be due to genetic effects of the CCL24+1272A→ G polymorphism, ht2 and ht6 haplotypes. Expand
Chapter 37 – Eosinophils
TLDR
During inflammatory conditions, eosinophils accumulate in their normal locations and in numerous other tissues, including the respiratory tract and secondary lymphoid organs, whereas in the gastrointestinal tract the α4 and β7 integrins appear to be important, suggesting that future therapeutics may include inhibitors of these Integrins. Expand
Comparison of plasma eotaxin family level in aspirin-induced and aspirin-tolerant asthma patients.
TLDR
This study shows that eotaxin-2 is differentially secreted in patients with asthma according to aspirin intolerance, and that secretion is not time-dependent in response to the APT in AIA and ATA patients. Expand
Chemokines and Chemokine Receptors: Their Role in Allergic Airway Disease
TLDR
It is now apparent that chemokines are potent leukocyte chemoattractants, cellular activating factors, histamine releasing factors, and regulators of homeostatic immunity, making them particularly important in the pathogenesis of airway inflammation in asthma. Expand
...
1
2
3
...

References

SHOWING 1-5 OF 5 REFERENCES
Eotaxin-2, a Novel CC Chemokine that Is Selective for the Chemokine Receptor CCR3, and Acts Like Eotaxin on Human Eosinophil and Basophil Leukocytes
TLDR
A novel human CC chemokine consisting of 78 amino acids and having a molecular mass of 8,778.3 daltons was isolated together with three minor COOH-terminally truncated variants with 73, 75, and 76 residues, which is functionally very similar to eotaxin and induced chemotaxis of eosinophils as well as basophils with typically bimodal concentration dependence. Expand
Human chemokines: an update.
TLDR
Of considerable interest is the recent discovery that some chemokines function as HIV-suppressive factors by interacting with chemokine receptors which, together with CD4, were recognized as the binding sites for HIV-1. Expand
Molecular and Functional Characterization of  Two Novel Human C-C Chemokines as Inhibitors of  Two Distinct Classes of Myeloid Progenitors
Two novel human β-chemokines, Ckβ-8 or myeloid progenitor inhibitory factor 1 (MPIF-1), and Ckβ-6 or MPIF-2, were discovered as part of a large scale cDNA sequencing effort. The MPIF-1 and MPIF-2Expand
PMS2-related genes flank the rearrangement breakpoints associated with Williams syndrome and other diseases on human chromosome 7.
TLDR
Mapping methodologies were used to determine the precise location of the human PMS2L genes, which were found to be present at at least three sites as part of duplicated genomic segments that flank the most common rearrangement breakpoints in Williams syndrome. Expand
Regional localization of 725 human chromosome 7-specific yeast artificial chromosome clones.
TLDR
The FISH mapping for 575 clones was accomplished by using "Alu-PCR" amplified YAC DNA against metaphase chromosome spreads made from a monochromosomal 7 human-mouse somatic cell hybrid line and there was excellent correlation between the map locations obtained for the 71 YACs localized with both methods. Expand