Assigning duplication events to relative temporal scales in genome-wide studies

@article{HuertaCepas2011AssigningDE,
  title={Assigning duplication events to relative temporal scales in genome-wide studies},
  author={Jaime Huerta-Cepas and Toni Gabald{\'o}n},
  journal={Bioinformatics},
  year={2011},
  volume={27 1},
  pages={
          38-45
        }
}
MOTIVATION In genome-wide analyses, the relative age of gene duplications is often estimated by measuring the rate of synonymous substitutions (dS) between paralogous sequences. On the other hand, recent studies have shown the feasibility of inferring, at genomic scales, the relative age of duplication events from the topology of gene family trees. This represents a promising alternative for large surveys requiring an automatic methodology to establish a timeline of duplication events and that… 

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