Assessment of zinc finger orientations by residual dipolar coupling constants.

  title={Assessment of zinc finger orientations by residual dipolar coupling constants.},
  author={Vickie Tsui and Lijun Zhu and Tom H-W Huang and Peter E. Wright and David A. Case},
  journal={Journal of biomolecular NMR},
  volume={16 1},
Residual dipolar coupling constants measured in anisotropic solution contain information on orientations between internuclear vectors and the magnetic field, providing long-range information that may help determine the relative orientations of distinct domains in biomolecules. Here we describe the measurement and use of residual dipolar coupling restraints in the refinement of the structure of the complex of DNA with three zinc fingers of transcription factor IIIA (TFIIIA), measured in a DMPC… CONTINUE READING

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