Assessment of urinary beta-core fragment of human chorionic gonadotropin as a new tumor marker of lung cancer.

@article{Yoshimura1994AssessmentOU,
  title={Assessment of urinary beta-core fragment of human chorionic gonadotropin as a new tumor marker of lung cancer.},
  author={Masahiro Yoshimura and Ryuichiro Nishimura and Akihiro Murotani and Yoshihiro Miyamoto and Toshitaro Nakagawa and Kazuo Hasegawa and Tamio Koizumi and Ken-ichiro Shii and S. El Baba and Noriaki Tsubota},
  journal={Cancer},
  year={1994},
  volume={73 11},
  pages={2745-52}
}
BACKGROUND Some patients with lung cancer have been found to have elevated levels of serum immunoreactive human chorionic gonadotropin (hCG)/hCG beta (IR-beta), but it is uncertain whether it would be valuable as a tumor marker. Recently, IR-beta has been demonstrated to consist of at least three different molecules, intact hCG, free hCG beta, and hCG beta-core fragment (beta-CF), in body fluids. In this study, the authors qualitatively analyzed IR-beta in the serum and urine of patients with… CONTINUE READING
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