Assessment of trabecular and cortical architecture and mechanical competence of bone by high-resolution peripheral computed tomography: comparison with transiliac bone biopsy

@article{Cohen2009AssessmentOT,
  title={Assessment of trabecular and cortical architecture and mechanical competence of bone by high-resolution peripheral computed tomography: comparison with transiliac bone biopsy},
  author={Adi Cohen and David W. Dempster and Ralph M{\"u}ller and X. Edward Guo and Thomas L Nickolas and X. Sherry Liu and Xian Zhang and A. J. Wirth and G. Harry van Lenthe and Thomas Kohler and Don J. McMahon and Hua Zhou and Mishaela R. Rubin and John P. Bilezikian and Joan M Lappe and Robert Roy Recker and Elizabeth Shane},
  journal={Osteoporosis International},
  year={2009},
  volume={21},
  pages={263-273}
}
We compared microarchitecture and mechanical competence parameters measured by high-resolution peripheral quantitative computed tomography (HR-pQCT) and finite-element analysis of radius and tibia to those measured by histomorphometry, micro-CT, and finite-element analysis of transiliac bone biopsies. Correlations were weak to moderate between parameters measured on biopsies and scans. HR-pQCT is a new imaging technique that assesses trabecular and cortical bone microarchitecture of the radius… CONTINUE READING