Assessment of topiramate's efficacy and safety in epilepsy

  title={Assessment of topiramate's efficacy and safety in epilepsy},
  author={Prem Parkash Gupta and Anup Kumar Thacker and Jamal Haider and Shilpi Dhawan and Neerjesh Pandey and Awanish Kumar Pandey},
  booktitle={Journal of neurosciences in rural practice},
OBJECTIVE To study the significance of topiramate (TPM) addition on seizure control in treatment of epilepsy. DESIGN A prospective open label add-on trial of TPM addition in patients with epilepsy was done. The events of baseline phase of 12 weeks followed by titration and maintenance phases were recorded. Assessment of the number of seizure and emergent adverse effects was done by a monthly visit for each case. MAIN OUTCOME MEASURES Reduction of more than 50% mean seizure frequency or… CONTINUE READING