Assessment of therapeutic quality control in a long-term anticoagulant trial in post-myocardial infarction patients.

@article{Azar1994AssessmentOT,
  title={Assessment of therapeutic quality control in a long-term anticoagulant trial in post-myocardial infarction patients.},
  author={Aida Azar and Jaap Willem Deckers and Frits R Rosendaal and P. F. M. M. van Bergen and Felix J. M. van der Meer and Jan Jonker and Ernest Bri{\"e}t},
  journal={Thrombosis and haemostasis},
  year={1994},
  volume={72 3},
  pages={347-51}
}
Various methods have been described to evaluate efficacy of anticoagulant therapy using the international normalized ratio (INR). We compared the following approaches: (1) total INR's or the most recent measurement; (2) percent time within therapeutic range, with INR changing directly or halfway between visits; and (3) total observation time assuming INR changing linearly. The study population comprised 1700 post myocardial infarction patients. Treatment comprised 3725 patient-years. There were… CONTINUE READING

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