Assessment of therapeutic potential by means of a probability model of antimicrobial action.

Abstract

The probability model of antimicrobial action is based on the definition of bactericidal activity as the probability, q, that any cell in the population will be killed during a division interval. Bacteriostatic activity is defined as a change in the division intervals (generation times) of the cells. A simplified, homogeneous model is used which assumes… (More)

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Cite this paper

@article{Schalkowsky1995AssessmentOT, title={Assessment of therapeutic potential by means of a probability model of antimicrobial action.}, author={S. Schalkowsky and Lawrence G. Hunt}, journal={The Journal of antimicrobial chemotherapy}, year={1995}, volume={35 1}, pages={31-52} }