Assessment of the reproducibility of baseline and hyperemic myocardial blood flow measurements with 15O-labeled water and PET.

@article{Kaufmann1999AssessmentOT,
  title={Assessment of the reproducibility of baseline and hyperemic myocardial blood flow measurements with 15O-labeled water and PET.},
  author={Philipp A. Kaufmann and Tomaso Gnecchi-Ruscone and Jeffrey T. Yap and O. Rimoldi and Paolo G. Camici},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1999},
  volume={40 11},
  pages={1848-56}
}
UNLABELLED PET with 15O-labeled water allows noninvasive quantification of myocardial blood flow (MBF) at baseline and during pharmacologically induced hyperemia to assess the coronary vasodilator reserve (CVR = hyperemic/baseline MBF). Despite widespread use of PET, its reproducibility during one study session has not been tested. Intravenous adenosine (Ado), a powerful coronary vasodilator with a very short decay time, is commonly used for the induction of hyperemia. However, it is not known… CONTINUE READING

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