Assessment of the radioprotective effects of amifostine and melatonin on human lymphocytes irradiated with gamma-rays in vitro.

@article{Kopjar2006AssessmentOT,
  title={Assessment of the radioprotective effects of amifostine and melatonin on human lymphocytes irradiated with gamma-rays in vitro.},
  author={Nevenka Kopjar and Slavica Mioci{\'c} and Snje{\vz}ana Rami{\'c} and Mirta Mili{\'c} and Tomislav Viculin},
  journal={Arhiv za higijenu rada i toksikologiju},
  year={2006},
  volume={57 2},
  pages={155-63}
}
Radioprotective effects of amifostine and melatonin as well as their ability to modulate the level of spontaneous and gamma-irradiation-induced genetic changes on human peripheral blood lymphocytes were investigated using the cytokinesis-block micronucleus (CBMN) assay and sister chromatid exchange (SCE). Parallel blood samples were pre-treated with amifostine, melatonin and their combination for 30 minutes. Negative controls were also included. After the treatment with radioprotectors, one… CONTINUE READING

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